Take your next dose at the regular time. Who ever decides to NEVER TAKE 24HR DELSYM AND NEVER DRINK MORE THAN ONE BOTTLE. Cough/cold combination products contain more than one ingredient. If you experience other effects, contact your pharmacist orhealthcare provider. Liquid preparations of this product may contain sugar and/or alcohol. Medically reviewed by Drugs.com. Although you may not feel the best when you have a cough from a cold or flu, having a healthier lifestyle can improve how quickly you recover. Generally, dosing will vary between every four to six hours by mouth, as needed, while youre feeling sick. Drowsiness, dizziness, blurred vision, upset stomach, nausea, nervousness, constipation, or dry mouth/nose/throat may occur. Brompheniramine, dextromethorphan, and pseudoephedrine is a combination medicine used to treat cough, runny or stuffy nose, sneezing, and watery eyes caused by allergies or the common cold. Adults and pediatric patients 12 years of age and over: 10 mL (2 teaspoonfuls) every 4 hours. You can opt-out at any time. If your doctor has prescribed this medication for you, take as directed by your doctor. What is Promethazine dm? In the United States, a bottle of Promethazine DM might cost around $12. Bromphen is an antihistamine that reduces the effects of natural chemical histamine in the body. The fluid will help loosen the mucus in your lungs. Ask your doctor or pharmacist how much acetaminophen is safe to take. Bromfed DM is a combination medicine used to treat cough, runny or stuffy nose, sneezing, itching, and watery eyes caused by allergies, the common cold, or the flu. Make a copy of your Promethazine DM prescription, and if possible, keep your medication in its original container from your pharmacy with your name on the label. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. Possible side effects of dextromethorphan include: Possible side effects of promethazine include: Contact your healthcare provider immediately if you develop any signs of a severe reaction. It is commonly marketed as its salt brompheniramine maleate. Brompheniramine Maleate, USP . This cookie is set by GDPR Cookie Consent plugin. Weight Loss for Health and Longevity, Science Reveals How Red Meat Harms the Heart, Flavored Vapes Still in Stores Despite Federal Ban, New COVID Antiviral Pills: What You Need to Know, Dr. Whyte's Book: Take Control of Your Cancer Risk, WebMD Loses Cherished Leader Kristy Hammam, Health News and Information, Delivered to Your Inbox, Treating Opioid Use Disorder With Medications, Constipated? The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Dextromethorphan is a cough suppressant that affects a certain part of the brain (cough center), reducing the urge to cough. This medication may interfere with certain lab tests (such as urine drug screening tests, urine 5-HIAA), possibly causing false test results. Older adults may be more sensitive to the effects of this drug, especially dizziness, drowsiness, mental/mood changes, constipation, trouble urinating, fast heartbeat, and blood pressure changes. Before having surgery, tell your doctor or dentist that you are taking this medication. Tell your doctor if your condition lasts or gets worse. Symptoms of overdose may include: nausea, vomiting, loss of appetite, sweating, stomach/abdominal pain, extreme tiredness, agitation, confusion, flushing, hallucinations, yellowing eyes/skin, dark urine, seizures. Since this medication also contains dextromethorphan, it should not be taken if you take any medicines in the monoamine oxidase inhibitor (MAOI) drug class. Otherwise, call a poison control center right away. This medication may pass into breast milk. Do not start, stop, or change the dosage of any medicines without your doctor's approval. Clin Pharmacol Ther. Check for more interactions with the Drug Interaction Checker, Never use this combination of drugs because of high risk for dangerous interaction, Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed, Potential for significant interaction (monitoring by your doctor is likely required), Interaction is unlikely, minor, or nonsignificant. Doing so can release all of the drug at once, increasing the risk of side effects. Some products have ingredients that could affect your heart rate or blood pressure. This medicine may contain aspartame. US residents can call their local poison control center at 1-800-222-1222. Oxygen, intravenous fluids, and other supportive measures should be employed as indicated. 1 Can you take Bromphen and promethazine together? This combination medication is used to temporarily treat symptoms caused by the common cold, flu, allergies, or other breathing illnesses (such as sinusitis, bronchitis). Children may be more sensitive to the effects of antihistamines. 30 mg, Dextromethorphan Hydrobromide, USP . Doing so can release all of the drug at once, increasing the risk of side effects. promethazine-dm oral , brompheniramine-pseudoephedrine oral Mechanism: unknown. Promethazine DM should be given to a pregnant person only if needed. Scientists are investigating a variety of drugs, including ones for anxiety and allergies, that might prevent the coronavirus from hijacking different cell systems to replicate itself. To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position. By blocking histamine, brompheniramine lowers inflammation (swelling) and relieves runny or itchy nose, sneezing, and watery eyes. How can I manage the side effects of Promethazine DM? If any of these effects persist or worsen, notify your doctor or pharmacist promptly. Drink plenty of fluids when you use this medication unless otherwise directed by your doctor. Among the antihistaminic effects, it antagonizes the allergic response (vasodilation, increased vascular permeability, increased mucus secretion) of nasal tissue. Do not exceed the recommended dose. Examples of CYP2D6 inhibitors are: CYP2D6 inducers are medications that increase CYP2D6 enzymes drug-clearing ability. . See additional information. Symptoms of overdose may include: agitation, confusion, flushing, hallucinations, large pupils, muscle twitching, seizures. To help prevent this effect, drink plenty of fluids unless otherwise directed by your doctor. Naloxone hydrochloride 0.005 mg/kg intravenously may be of value in reversing the CNS depression that may occur from an overdose of dextromethorphan. . Promethazine is a medication used to manage and treat allergic conditions, nausea and vomiting, motion sickness, and sedation. Promethazine DM should not be used in people that are in a coma. This means that any drug that impacts CYP2D6 enzymes might not be cleared as quickly. Do not store in the bathroom. Other medicines that impact how CYP2D6 works may also change how well Promethazine DM works. Make sure lab personnel and all your doctors know you use this drug. On the other hand, dextromethorphan will act as a cough suppressant. Drowsiness, dizziness, dry mouth/nose/throat, headache, upset stomach, constipation, or trouble sleeping may occur. Take this medication by mouth with or without food or as directed by your doctor. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. In Canada - Call your doctor for medical advice about side effects. What drug class is Bromfed? Precautions against aspiration must be taken, especially in infants and small children. Do not take this product for several days before allergy testing because test results can be affected. Management of chronic refractory cough in adults. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Drug interactions may change how your medications work or increase your risk for serious side effects. Most MAO inhibitors should also not be taken for two weeks before and after treatment with this medication. But opting out of some of these cookies may affect your browsing experience. Brompheniramine maleate is a histamine antagonist, specifically an H1-receptor-blocking agent belonging to the alkylamine class of antihistamines. All rights reserved. However, Bromfed DM is FDA approved, and. For example, Robitussin and Promethazine DM should NOT be taken together; they both have the same active ingredient, and you could risk an overdose. In a pleasant, aromatic vehicle. Brompheniramine also has anticholinergic (drying) and sedative effects. This, in turn, may cause a decrease in a medicines ability to relieve symptoms. What is the difference between bromfed dm cough syrup and promethazine? If it is near the time of the next dose, skip the missed dose. It has two active ingredients: Dextromethorphan and promethazine. How much does Promethazine DM cost? Treasure Island (FL): StatPearls. Many people using this medication do not have serious side effects. Discuss the risks and benefits with your doctor. System: Urinary frequency, difficult urination. Store at room temperature away from light and moisture. 2 mg, Pseudoephedrine Hydrochloride, USP . only. Bromphen is used to treat runny nose, sneezing, itching, and watery eyes caused by allergies, the common cold, or the flu. Keep out of direct sunlight while taking this medicine. Enter your medication into the WebMD interaction checker, Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Fitness vs. It affects the signals in the brain that trigger cough reflex. Safety and effectiveness in pediatric patients below the age of 6 months have not been established (see DOSAGE AND ADMINISTRATION). This interaction is more likely in certain predisposed patients only. This cookie is set by GDPR Cookie Consent plugin. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. You may report side effects to theFood and Drug Administration (FDA)atfda.gov/medwatchor 800-FDA-1088. One ingredient in this product is acetaminophen. Does bromphen/pseudo/dextro hbr syrup have alcohol? Caution is advised if you have diabetes, alcohol dependence, liver disease, phenylketonuria (PKU), or any other condition that requires you to limit/avoid these substances in your diet. Do not use this product to make a child sleepy. (473ml) - NDC 62135-302-47 - Label. The cookie is set by the GDPR Cookie Consent plugin and is used to store whether or not user has consented to the use of cookies. Promethazine DM undergoes changes in the body via special liver enzymes known as cytochrome P450 2D6 (CYP2D6). Do not prepare a supply for future use. Keep all regular medical and laboratory appointments. Talk to your pharmacist for more details. Chewable forms of this medication should be chewed thoroughly before swallowing. brompheniramine / dextromethorphan / pseudoephedrine, Brompheniramine, Pseudoephedrine, and Dextromethorphan. European Journal of Internal Medicine. The following information includes only the average doses of this medicine. Bromfed DM will not treat a cough that is caused by smoking, asthma, or emphysema. Hyperpyrexia, hypotension, and death have been reported coincident with the coadministration of MAO inhibitors and products containing dextromethorphan. Old antibiotics should also be discarded, he said. If you are taking this product on a regular schedule and miss a dose, take it as soon as you remember. You can reduce the risk of constipation with a healthy diet consisting of ample fiber and water. Promethazine is an antihistamine and blocks histamine receptors. This medication may interfere with certain medical/lab tests (such as brain scan for Parkinson's disease, urine drug screening tests), possibly causing false test results. What's important is that you take it as soon as you remember. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use. Talk to your doctor if you are using marijuana (cannabis). Verywell Health's content is for informational and educational purposes only. Some products that may interact with this drug are: antihistamines applied to the skin (such as diphenhydramine cream, ointment, spray), ketoconazole, levoketoconazole, rolapitant. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. Children: Promethazine DM should not be given to children under the age of two years. Tell your doctor or pharmacist if you are taking other products that cause drowsiness such as opioid pain or cough relievers (such as codeine, hydrocodone), alcohol, marijuana (cannabis), drugs for sleep or anxiety (such as alprazolam, lorazepam, zolpidem), muscle relaxants (such as carisoprodol, cyclobenzaprine), or other antihistamines (such as cetirizine, diphenhydramine). 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