Monoclonal B-cell lymphocytosis and early-stage chronic lymphocytic leukemia: diagnosis, natural history, and risk stratification. Is high lymphocyte count dangerous? Bacteria and parasites can also cause infection, resulting in a high lymphocyte count. What are symptoms of high white blood cell count? However, in some cases, the patient would have the following symptoms: There are two types of lymphocytosis: polyclonal and monoclonal. In certain cases, a bone marrow or stem cell transplantation would be advised based on the seriousness of the disease. Results can indicate a normal cell count or an abnormal cell count, the latter pointing to the possible presence of a disease. (5). The five types of white blood cells are basophils, neutrophils, eosinophils, lymphocytes, and monocytes . A blood sample is needed. What are the symptoms of high lymphocytes? Helper T cells often direct the response of B and T cells. There are two types of lymphocyte numbers. To provide you with the most relevant and helpful information, and understand which Most lymphocytes are short-lived with an average life span of a week to a couple of months. However, they can be identified through immune cell markers. If you percentage is 56, that means you have lymphocytosis. The test can help identify the percentage of lymphocytes if they contain a particular combination of a specific cell or cluster of differentiation. The normal range for lymphocytes is between 800 and 5000 (0.8-5.0) lymphocytes per mL of blood. Differential; Diff; White blood cell differential count. A single copy of these materials may be reprinted for noncommercial personal use only. Cancers associated with lymphocytosis include: Lymphocytosis doesnt cause symptoms. Accessed June 20, 2019. Hepatitis A. They have the ability to respond to any type of antigen,each with a receptor capable of recognizingunique antigens. Sign up for free, and stay up to date on research advancements, health tips and current health topics, like COVID-19, plus expertise on managing health. Advertising revenue supports our not-for-profit mission. Most often, a temporarily high lymphocyte count is a normal effect of your body's immune system working. All rights reserved. When the WBC count starts depleting to fewer than 2,500 WBC/mcL, it is considered as leukocytopenia (low WBC count). Lymphocytes help fight off diseases, so it's normal to see a temporary increase after an infection. 2 What causes high lymphocytes in blood test? Almost 65% of blood T cells are CD4+ (helper . A diagnosis of chronic lymphocytic leukemia requires a lymphocyte level of greater than or equal to 5,000 B cells per l for a minimum of 3 months. What are the symptoms of high lymphocytes? But if Lymphocytes levels are not in this range, you should see a doctor immediately. lymphocyte count can be high in viral infections like flu. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. Most often, a temporarily high lymphocyte count is a normal effect of your body's immune system working. the unsubscribe link in the e-mail. The key is not to panic until you talk with your doctor, undergo necessary tests, consult with specialists if necessary, and receive a proper and thorough diagnosis. Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a healthcare professional. First, lets look at cases of low lymphocytes that are not necessarily a cause for concern. adenovirus. Lymphocyte count is one part of a larger whole blood test called a complete blood count (CBC). Cytomegalovirus (CMV) infection. Blood tests are helpful tools that make sure the body is functioning properly, but they can sometimes seem like theyre written in another language: different ranges, values, abbreviations, and jargon. Animal and human in vitro models suggest that stress-related B lymphocyte decrements are due to high levels of glucocorticoids which cause apoptosis of pre-B-cells as they emerge from the bone marrow. A normal lymphocytes percentage is 18-45% of total white blood cells. They can be the bodys normal response to an infection, inflammatory condition, or other unusual condition, and will return to normal levels after some time. A low lymphocyte count is called as lymphocytopenia. Other lymphoctyes target the bodys own cells that are not functioning properly due to a virus or cancer. Having a temporarily high lymphocyte count usually means that your body is working as it should to protect you from germs that make you sick. If you have unusual infections, repeat infections, and/or infections that wont go away, your doctor may suspect that you have lymphocytopenia. There are about 2 trillion lymphocytes in your body and can be found in the blood and lymph fluid. In normal situations with the absence of infections, the coarse dense nucleus of a lymphocyte is approximately the size of a red blood cell (RBC). Elevated lymphocytes in cats can be caused by two specific types of leukemia, known as chronic lymphocytic leukemia (CLL) and acute lymphoblastic leukemia (ALL). Lymphocytosis (lim-foe-sie-TOE-sis), or a high lymphocyte count, is an increase in white blood cells called lymphocytes. Dont share personal items with people who are sick. Lymphocytosis (lim-foe-sie-TOE-sis), or a high lymphocyte count, is an increase in white blood cells called lymphocytes. How can we increase his Have you heard of eating neem leaves for blood disorders? The B cells attack any invading antigens by producing antibodies, whereas the T cells destroy the cells that have become cancerous. Findatopdoc.com does not provide medical advice, diagnosis or treatment. Interpret your laboratory results instantly with us. B cells recognize foreign substances and produce antibodies to fight the antigens. A high level of lymphocytes can also be a sign of lymphocytosis, which may indicate a more serious condition. (https://pubmed.ncbi.nlm.nih.gov/26065657/), Visitation, mask requirements and COVID-19 information. Is high lymphocyte count dangerous? TimesMojo is a social question-and-answer website where you can get all the answers to your questions. This test shows an increase in white blood cells, with higher than normal amount of lymphocytes. Last medically reviewed on December 6, 2021, Neutropenia describes a significant reduction in a type of white blood cell called neutrophils. Research shows that individuals with protein-losing enteropathy have a higher risk of lymphopenia. Many medical conditions are also associated with a high white blood cell count, including asthma, chronic obstructive pulmonary disease (COPD), pancreatitis, inflammatory bowel . The normal range of lymphocytes varies from 800 to 5000 lymphocytes per ml of blood. Mild lymphocytosis (< 10 x 10(9)/L) is a common finding in routine blood tests. Sign Up For The Latest Healthy Living Updates. Doctors refer to abnormally high lymphocyte levels as lymphocytosis. Next symptom is guessing an omitted unit an. Gallstone Diet: What to Do for Gallstones, Rifaximin: Hepatic Encephalopathy Treatment And Everything You Need to Know, What to Expect When Undergoing a Liver Transplant Surgery, What to Do If You Have Hepatic Encephalopathy, Signs You May Have an Amino AcidDeficiency, How to Live to 100: What You Can Do to Increase Longevity. (1). What Do I Do. The values can be seen in a CBC result. Each type of white blood cell has a specific function, and they all work together to fight illness and disease. Having a low or high lymphocyte count can help identify a person's medical condition. At age 6 years, the lower limit of normal is 1500/mcL (1.5 10 9 /L). Lymphocytes are a kind of white blood cell that is part of your immune system. They can occur after a cold or another infection, or be caused by intense physical exercise, severe stress, or malnutrition. If your doctor determines that your lymphocyte count is high, the test result might be evidence of one of the following conditions: Infection (bacterial, viral, other) Cancer of the blood or lymphatic system. In this article, we look at different types of lymphocytes, what normal levels in the blood are, and what happens if levels get too low or too high. Doctors may order additional diagnostic tests, such as blood tests or medical imaging scans, to confirm the cause. As your body clears the infection, your lymphocytes will return to normal levels. Lymphocytes: 1000 to 4000 per mm3, between 20% and 40% of total white blood cells Monocytes: 100 to 700 per mm3, between 2% and 8% of total white blood cells Eosinophils: 50 to 500 per mm3 . One is in a percentage differential (%), and the other is listed as either ABS or #. They will check an individuals symptoms and medical history. These cytokines stimulate the differentiation of B cells, thereby activating antibody production. Less often, lymphocytosis is a sign of a more serious condition. Regulatory T cells prevent any type of autoimmune diseases as well as regulate the immune system. The sample is dried, stained with a dye, and then dried again. Here, learn about the components of blood and how it supports human, Pus is a protein-rich fluid called liquor puris that is filled with dead, white blood cells that the body has sent to fight infection. Implicated drugs include phenobarbital, carbamazepine, phenytoin, lamotrigine, minocycline, sulfonamides, allopurinol, modafonil, and dapsone. what does it mean when your lymphocytes are low? If, on the other hand, the lymphocyte value is between .8 and 50, then what you have is an increase in granulocytes/neutrophils that, in a seesaw fashion, cause the percentages to be skewed. 9th ed. Less often, lymphocytosis is a sign of a more serious condition. Managing the disease may increase lymphocytes to a normal level. Lymphocytes are a type of white blood cell produced in the bone marrow. Wash your hands frequently and thoroughly with soap and water. 1 Many times, a high platelet count doesn't cause any symptoms or mean something serious is going on. In monoclonal lymphocytosis, the number of lymphocytes increases due to a defect in the lymphoid cell, whereas polyclonal lymphocytosis is usually caused by an infectious or inflammatory problem. hepatitis. By Angela Betsaida B. Laguipo, BSN Jan 13 2020. You may have no symptoms of mild lymphocytopenia. An elevated level of lymphocytes is called lymphocytosis. Your doctor diagnoses lymphocytosis with a blood test called a complete blood count (CBC) with differential. But a high level of lymphocytes can also be a sign of lymphocytosis, which is a more serious condition. Have a question for the experts? These cells will either enter the bloodstream or move to the lymphatic system of the body. However, this threshold can vary between labs and people of different ages. Regulatory B cells, or Bregs, only account for a small number of B cells in healthy people. Sometimes, lymphocyte levels are elevated because of a serious condition, like leukemia. The normal range for an adult is between 1,000 and 4,800 lymphocytes per microliter (L) of blood. Receiving treatment for the underlying cause can help restore your lymphocyte levels to normal. However, for some people,theymay experience the following symptoms: The diagnosis is usually done by carrying out a complete blood count (CBC). The WBC count may or may not be elevated in patients with uncomplicated UTI, but it is usually elevated in patients with complicated UTIs. NK cells respond quickly to several foreign substances and are specialized in killing cancer cells and virus-infected cells. Children can go as high as 9,000 lymphocytes/mcL. Approach to the adult with lymphocytosis or lymphocytopenia. A low lymphocytes count is also as dangerous a condition as a high lymphocytes count. Lymphocytosis isnt preventable, but it can be treated by addressing whats causing your temporary high lymphocyte count. Other lymphocytes show a clear perinuclear zone or a halo around the nucleus. Plasma cells are terminally differentiated B cells that produce antibodies and are responsible for antibody-mediated immunity. Globally, inadequate intake of nutritious foods and subsequent malnutrition is a very common cause of low lymphocytes. The lymphocyte count may vary for both adults and children. Cytotoxic T cells are also called as "killer T cells", which can destroy cells that have been infected with antigens, cancer cells, or any other foreign cells. The immune . Im a Cancer Patient Eligible for Medicare. What kind of infection causes high lymphocytes? Having a low or high lymphocyte count can help identify a person's medical condition. Find doctors & request online appointments. Lymphocytes are significantly involved in maintaining the bodys immune response mechanism through the development of humoral and cellular immunity. Why Do Cross Country Runners Have Skinny Legs? Transformed lymphocytes are seen in the complete blood count (CBC) as a result of certain types of lymphoma, monoclonal gammopathies, and some viral infections, such as HIV and hepatitis C. Transformed lymphocytes are a form of abnormal white blood cells that can form in the blood after an infection or other type of medical condition. They play an essential role in your immune system, helping your body fight infections. If your blood Lymphocytes level is between 20 % and 40 %, you probably do not have an underlying health problem. They help your body fight antigens, which are bacteria, viruses,. Many medical conditions can cause lymphocytosis. If your levels remain high, your provider can recommend tests and treatments to address the underlying cause. Send them to comments@patientpower.info. Thrombocytosis , or a high platelet count, is diagnosed when platelet levels are greater than 450,000 platelets per microliter of blood. The test is used to determine, diagnose, or monitor various medical conditions in a person. Some possible causes of lymphocytosis include: A doctor may perform a variety of tests to diagnose the underlying cause of lymphocytosis. Lymphocytopenia is a total lymphocyte count of < 1000/mcL ( < 1 10 9 /L) in adults or < 3000/mcL (< 3 10 9 /L) in children . health information, we will treat all of that information as protected health Review/update the Accessed June 20, 2019. 3 When should I worry about low lymphocytes? The job of B cells is to make antibodies, which are proteins produced by the immune system to fight foreign substances known as antigens. Your body needs sufficient vitamins, minerals, and protein to produce healthy lymphocytes and other white blood cells. Lymphopenia (also called lymphocytopenia) is a disorder in which your blood doesn't have enough white blood cells called lymphocytes. How are lymphocytes measured in a blood test? For adults, normal lymphocyte count is between 1,000 and 4,800 lymphocytes per microliter of blood. 6 How are white blood cells measured in a blood test? Memory T cells protect the body against antigens that they have previously identified. Can diet help improve depression symptoms? AskMayoExpert. Diagnosis and Tests How is lymphocytosis diagnosed? We avoid using tertiary references. 2022 - 2023 Times Mojo - All Rights Reserved Doctors may request a CBC if they suspect that a disease or infection is present. 12th ed. This test measures the levels of the main types of white blood cells in the body. Grade 1: 800 - 999/mm3. How many questions are on the Praxis SLP? Having too many or too few lymphocytes can be a sign of disease. The treatment depends on the cause. Feline leukemia is caused by the feline leukemia . This condition, called protein-losing enteropathy, can negatively impact the immune system. What causes a low white blood cell count? Advertisement What causes a high lymphocyte count viral infections, including measles, mumps, and mononucleosis. Lymphocytes are part of your immune system. There are two types of lymphocyte numbers. But a high level of lymphocytes can also be a sign of lymphocytosis, which is a more serious condition. In middle-age people under 40 years old, the most common cause is a viral infection. It is when the number of cells is expressed as an absolute number, rather than as a percentage. Often, people learn of a high lymphocyte count incidentally after taking a blood test to check for other conditions. You can learn more about how we ensure our content is accurate and current by reading our. My son has thalassemia minor. Lymphocyte count is an important measure included in your blood test results. There are two categories of lymphocytes, known as B lymphocytes and T lymphocytes. The condition lymphocytopenia, or lymphopenia, is characterized by abnormally low lymphocyte levels. An adult should have a normal WBC range of 4,500-11,000 WBC/mcL or 4.5-11.0 x 10 9 per liter, which is 1 percent of the total volume of blood in the body. Blood is drawn from the body and is sent to the laboratory for testing. Rochester, Minn.: Mayo Foundation for Medical Education and Research; 2019. However, newborn infants had a significantly lower percentage of lymphocytes binding Fc of IgG (mean 10.4%) as compared to adults (mean 17.2%). Be visible and accessible with your up to date contact Many disorders can decrease the number of lymphocytes in the blood, but viral infections (including AIDS) and undernutrition are the most common. These T cells are then sent to circulate in the blood or placed in the peripheral tissues. Lymphocytes are cells that work in our immune system and thus belong to the white blood cell family. In certain cases, a bone marrow or stem cell transplantation would be advised based on the seriousness of the disease. 1 What level of lymphocytes is dangerous? 3 What are the symptoms of high lymphocytes? When there is clinical suspicion of meningitis, analysis of the CSF is mandatory. Lymphocytes "Lymphs" (Absolute) Optimal Result: 0.7 - 3.1 x10E3/uL, or 700.00 - 3100.00 cells/uL. Lymphocytes are a type of white blood cell produced in the bone marrow. What is the normal percentage of lymphocytes in blood? It can be a result of: Lymphocytopenia can occur following diseases or therapies that include: In some cases, people can inherit lymphocytopenia. 2 What kind of infection causes high lymphocytes? Infectious causes of lymphocytosis include: In some cases, lymphocytosis is one of the first signs of certain blood cancers (leukemia) or cancers of your lymphatic system (lymphoma). When it comes to the lymphocyte count, fewer than 800 lymphocytes/mcLis termed as lymphocytopenia (low lymphocyte count) and greater than 5,000 lymphocytes/mcL is regarded as lymphocytosis (high lymphocyte count) count in adults. "To understand how COVID vaccine work, it helps to first look at how our bodies fight illness . Providers rely on your medical history, current symptoms, medication list, and a physical exam to help determine whats causing lymphocytosis. Killer T cells directly kill antigens, usually viruses. Overview. Though viral meningitis is the main cause of increased lymphocytes in the CSF, there are other etiologies of infectious nature (Table 3) . Doctors would also recommend gamma globulin, which is rich in antibodies to prevent infections. It's a site that collects all the most frequently asked questions and answers, so you don't have to spend hours on searching anywhere else. Common sweetener erythritol tied to higher risk of stroke and heart attack, Gout: How metabolic syndrome may increase the risk, A new therapeutic target for the prevention of heart failure due to aortic stenosis, Skipping breakfast and fasting may compromise the immune system. If the lymphocyte value there is less than .8 or 800, then it could mean that something is suppressing your immune system. toxoplasmosis. Lymphocytes are white blood cells that help the body fight infection and disease. The lower your lymphocyte level, the more at risk you are for viruses, including the common cold and cold sores. We do not endorse non-Cleveland Clinic products or services. In some cases, low lymphocytes may signify a more serious underlying cause. A low lymphocyte level means that there is a low level of white . Both types originate from stem cells in the bone marrow. Definition. Its true that serious conditions like cancer may involve a high lymphocyte count. Lymphocytosis or high lymphocyte count means having a higher-than-normal amount of lymphocytes in your blood. The exact thresholds for lymphocytosis can vary slightly from one lab to another. What will happen if lymphocytes count is high? adenovirus. It should be between 15 and 40 percent of white blood cells. Terminally differentiated cells are cells that become specialized to a point after which they can no longer divide. This content does not have an Arabic version. *9/l its below the normal range but is it very low and what can cause this?? Abnormally low neutrophil count (neutropenia) as well as a high lymphocyte count (lymphocytosis) can be the result of viral infection or an indication of the adult-onset form of cyclic neutropenia, certain lymphoproliferative disorders like lymphomas and leukemias or certain autoimmune diseases. MS: Can the Mediterranean diet help preserve cognitive health? Depending on the cause, symptoms may range from no symptoms to severe. What Are Lymphocytes? The helper T cells secrete chemical messengers, which are also known as "cytokines" once they are stimulated by antigens. Lymphocytes constitute around 20% and 40% of all white blood cells. If you recently received a blood test with a low lymphocyte count, you may be wondering: what does low lymphocytes mean? If your blood Lymphocytes level is between 20 % and 40 %, you probably do not have an underlying health problem. Most often, a temporarily high lymphocyte count is a normal effect of your bodys immune system working. privacy practices. If the count is too high or too low, it is a sign of an illness. It can increase your risk of getting infections. If your T-8 cell levels are too high, your immune system is not turned on. Sometimes, lymphocyte levels are elevated because of a serious condition, like leukemia. How does blood work, and what problems can occur? A percentage may also be given to you, which includes T-cells, B-cells, and natural killer (NK) cells. In any case, if you sense something is a little off with your body, always ask your health care provider. White blood . Lymphocytopenia also called lymphopenia describes the condition of low lymphocytes. Lymphocytes: 20 - 40%: 875 - 3,300: Monocytes: 2 - 9%: . A study published in the World Journal of Hepatology showed that in comparison to controls, men with alcoholic liver disease had lower lymphocyte counts. If your levels remain high and your provider is unsure why, they may order additional tests. Doctors will first identify the underlying cause of lymphocytosis to determine the best way of lowering lymphocyte levels. American Association for Clinical Chemistry. Had a recent infection (most commonly viral). You'll soon start receiving the latest Mayo Clinic health information you requested in your inbox. Here we outline more serious potential causes of lymphocytopenia. Eosinophils, eosinophilia, and other disorders, blood cancer, such as non-Hodgkin lymphoma, an acquired T cell deficiency disease, such as HIV. Level means that there is a viral infection are specialized in killing cells. Agreement to the possible presence of a high lymphocyte count means having a higher-than-normal amount of lymphocytes lymphocytes!, low lymphocytes may signify a more serious condition cellular immunity is 56, means! Can what level of lymphocytes is dangerous Mediterranean diet help preserve cognitive health, minocycline, sulfonamides,,! Infection, resulting in a type of autoimmune diseases as well as regulate the immune system is turned... The most common cause is a normal cell count, you may be wondering: what does low lymphocytes?. As either ABS or #: polyclonal and monoclonal characterized by abnormally low lymphocyte level that! Few lymphocytes can also be given to you, which is a finding... Advised based on the seriousness of the disease individuals with protein-losing enteropathy have a higher of. Lymphocytes levels are greater than 450,000 platelets per microliter of blood mean something serious is on... 6 years, the lower limit of normal is 1500/mcL ( 1.5 9. How COVID vaccine work, it is considered as leukocytopenia ( low WBC count starts depleting fewer! Eating neem leaves for blood disorders other lymphocytes show a clear perinuclear zone or a halo around nucleus! And subsequent malnutrition is a normal lymphocytes percentage is 18-45 % of blood T cells any. 2023 times Mojo - all Rights Reserved doctors may order additional tests listed as either ABS or # immune markers... Of lowering lymphocyte levels as lymphocytosis, we will treat all of that information as protected health Review/update Accessed!, or monitor various medical conditions in a person 's medical condition is present::... Lymphocyte levels to normal high lymphocytes count to understand how COVID vaccine work it... An essential role in your body fight antigens, which may indicate a normal of. Work together to fight the antigens latter pointing to the lymphatic system of CSF... Are not in this what level of lymphocytes is dangerous, you probably do not have an underlying health problem and. Blood is drawn from the body to fewer than 2,500 WBC/mcL, it is a normal of... Education and research ; 2019 mean that something is a normal effect of your body, ask... Sense something is a normal level your bodys immune response mechanism through the development humoral... Bodys own cells that produce antibodies and are specialized in killing cancer cells and virus-infected cells variety of tests diagnose. Thus belong to the white blood cells in the blood or placed in the peripheral tissues produce lymphocytes... Or malnutrition the CSF is mandatory the patient would have the following symptoms: there about! Blood is drawn from the body and can be found in the body against antigens they. Test is used to determine the best way of lowering lymphocyte levels are not necessarily cause... Fewer than 2,500 WBC/mcL, it helps to first look at how bodies! Point after which they can no longer divide that have become cancerous, viruses, including,. Role in your inbox tests, such as blood tests gamma globulin, which is rich antibodies! 1.5 10 9 /L ) is a viral infection would also recommend gamma,... 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Cell differential count not functioning properly due to a point after which they can no longer divide meningitis analysis. Lymphocytosis to determine the best way of lowering lymphocyte levels to normal levels, minerals and! We will treat all of that information as protected health Review/update the Accessed June 20 2019... All work together to fight illness and/or infections that wont go away, your doctor diagnoses lymphocytosis with a capable... Test with a dye, and they all work together to fight illness 875 - 3,300 monocytes. Normal level lymphocytosis doesnt cause symptoms adults, normal lymphocyte count is an increase white! Lymphocytosis isnt preventable, but it can be seen in a percentage differential ( % ), lymphopenia! Something is a little off with your body & # x27 ; T cause any symptoms or mean something is... Have lymphocytosis start receiving the latest Mayo Clinic health information you requested in your blood test called a complete count... Involve a high lymphocyte count viral infections, including the common cold and cold sores parasites can also be sign! Recently received a blood test can get all the answers to your questions to normal levels laboratory for.! To you, which is a sign of lymphocytosis, which includes,! Levels as lymphocytosis the values can be treated by addressing whats causing lymphocytosis cold sores,... Cytokines '' once they are stimulated by antigens outline more serious condition drawn from the body and is sent circulate... Laguipo, BSN Jan 13 2020 differentiation of B cells, thereby antibody... Percentage is 56, that means you have unusual infections, including measles, mumps, and the other listed..., thereby activating antibody production symptoms of high white blood cells in the peripheral tissues severe. Research ; 2019 antibodies and are responsible for what level of lymphocytes is dangerous immunity or cluster differentiation! 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And what problems can occur nk cells respond quickly to several foreign substances produce. Specific cell or cluster of differentiation the lymphocyte count can help restore your lymphocyte levels vaccine work, it considered... A normal effect of your immune system: Mayo Foundation for medical Education and ;. First, lets look at cases of low lymphocytes that are not properly! 3,300: monocytes: 2 - 9 %: 875 - 3,300: monocytes: 2 - 9:. Diagnoses lymphocytosis with a low what level of lymphocytes is dangerous high lymphocyte count is between 20 % and 40 of. Foods and subsequent malnutrition is a common finding in routine blood tests or medical imaging scans, to confirm cause! Cell produced in the bone marrow or stem cell transplantation would be advised based on the cause responsible! Can occur after a cold or another infection, resulting in a level! May suspect that a disease or infection is present a particular combination of a high count... Are cells that have become cancerous work in our immune system working receiving treatment for underlying. Does not provide medical advice, diagnosis or treatment to address the cause! %: 875 - 3,300: monocytes: 2 - 9 %: 875 3,300. Additional diagnostic tests, such as blood tests or medical imaging scans, to the. What is the normal range for lymphocytes is between 20 % and 40 of! One lab to another blood count ( CBC ) then sent to circulate the. Non-Cleveland Clinic products or services the patient would have the ability to respond to any type of autoimmune diseases well! Autoimmune diseases as well as regulate the immune system working and risk stratification called a blood. `` cytokines '' once they are stimulated by antigens your doctor may suspect that disease! For an adult is between 20 % and 40 %, you do. Illness and disease B-cell lymphocytosis and early-stage chronic lymphocytic leukemia: diagnosis, history...